A bacteriocin of Actinobacillus actinomycetemcomitans
نویسندگان
چکیده
منابع مشابه
Purification and biochemical properties of a bacteriocin from Actinobacillus actinomycetemcomitans.
Extracts of certain strains of Actinobacillus actinomycetemcomitans are inhibitory to strains of Streptococcus sanguis such as S. sanguis ATCC 10556. The isolation of a protein from an A. actinomycetemcomitans sonic extract which copurified with the inhibitory activity was accomplished by preparative isoelectric focusing, Sephadex G-100 gel filtration chromatography, and preparative polyacrylam...
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Actinobacillus actinomycetemcomitans is a gram-negative coccobacillus which is a very rare cause of bacterial endocarditis. Preexisting cardiac lesions are a main contributing factor, and antibiotic prophylaxis has long been felt necessary before dental or other manipulation to prevent endocarditis. Penicillin in combination with an aminoglycoside has been the most often used treatment regimen....
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We report what may be the first documented case of an anterior mediastinal abscess due to infection by Actinobacillus actinomycetemcomitans. This small, fastidious Gram-negative coccobacillus is a normal component of the oral flora of healthy individuals,' but rarely a human pathogen. It was first described in 1912 by Klinger2 in association with actinomycosis and has since been identified as t...
متن کاملCharacterization of serologically nontypeable Actinobacillus actinomycetemcomitans isolates.
Our previous studies have shown that Actinobacillus actinomycetemcomitans isolates of a given arbitrarily primed PCR (AP-PCR) genotype belong to the same serotype (of serotypes a through e). In the present study we investigated whether the AP-PCR genotypes of nonserotypeable A. actinomycetemcomitans isolates match those of the serotypeable isolates. The isolates were additionally characterized ...
متن کاملSecretion of RTX leukotoxin by Actinobacillus actinomycetemcomitans.
Actinobacillus actinomycetemcomitans, the etiologic agent for localized juvenile periodontitis and certain other human infections, such as endocarditis, expresses a leukotoxin that acts on polymorphonuclear leukocytes and macrophages. Leukotoxin is a member of the highly conserved repeat toxin (RTX) family of bacterial toxins expressed by a variety of pathogenic bacteria. While the RTX toxins o...
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ژورنال
عنوان ژورنال: Infection and Immunity
سال: 1987
ISSN: 0019-9567,1098-5522
DOI: 10.1128/iai.55.3.686-691.1987